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ICONCL2162 FTY720(Fingolimod HCl) (162359-56-0)
 
 
Catalog No.: CL2162
CAS No.: 162359-56-0
Synonym: Fingolimod HCl
Chemical Name:

2-Amino-2-[2-(4-octylphenyl)ethyl]-1,3-propanediol HCl

Molecular Formula:

C19H33NO2.HCl

Molecular Weight: 343.93
 
Technical Data:
Appearance: White to off-white crystalline powder
Solubility: Soluble in DMSO
Purity: >99%
Storage: at -20℃
Original QC Data:
Shipping Conditions: Ambient Temp.
 
Price and Availability of FTY720(Fingolimod HCl):

Size

Price

Stock

250 mg 

USD 126

In stock 

500 mg 

USD 186

In stock 

1 g 

USD 266

In stock 

Contact us for competitive discounts on bulk quantities

 
Biological Activity:

Novel immune modulator that alters migration and homing of lymphocytes. Acts as a potent agonist of sphingosine 1-phosphate receptors (S1P) after phosphorylation by sphingosine kinase. Also inhibits cytosolic phospholipase A2 independently of sphingosine 1-phosphate receptors.

 
References:
Wallington-Beddoe CT, et al. Disparate in vivo efficacy of FTY720 in xenograft models of Philadelphia positive and negative B-lineage acute lymphoblastic leukemia. PLoS One. 2012, 7(5), e36429.
 
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