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ICONCL1068 Cyclosporin C (59787-61-0)
 
 
Catalog No.: CL1068
CAS No.: 59787-61-0
Synonym: Thr2-cyclosporine
Chemical Name:

Cyclo[L-alanyl-D-alanyl-N-methyl-L-leucyl-N-methyl-L-leucyl-N-methyl-L-valyl-3-hydroxy-N,4-dimethyl-L-2-amino-6-octenoyl-L-threonyl-N-methylglycyl-N-methyl-L-leucyl-L-valyl-N-methyl-L-leucyl]

Molecular Formula:

C62H111N11O13

Molecular Weight: 1218.63
 
Technical Data:
Appearance: Colorless Prismatic needles
Solubility: Soluble in ethanol and DMSO
Purity: >95%
Storage: at room temperature
Original QC Data:
Shipping Conditions: Ambient Temp.
 
Price and Availability of Cyclosporin C:

Size

Price

Stock

1 mg 

USD 266

In stock 

5 mg 

USD 666

In stock 

Contact us for competitive discounts on bulk quantities

 
Biological Activity:

A fungal metabolite possessing potent immunosuppressive properties. It inhibits the T-cell receptor signal transduction pathway via the formation of cyclosporin A-cyclophilin complex that inhibits calcineurin (protein phosphatase 2B). Inhibits nitric oxid.

 
References:
Moussaïf M  et al. Cyclosporin C is the main antifungal compound produced by Acremonium luzulae. Appl Environ Microbiol 63:1739-43 (1997).
 
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