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Biological Activity:
Selective 5-HT4 receptor agonist; a gastroprokinetic agent for the treatment of constipation and irritable bowel syndrome; showed memory-enhancing effects in mice through modulation of cholinergic pathways; hence an indication of potential as Alzheimer's disease therapy.
References:
Bouras EP, et al. Selective stimulation of colonic transit by the benzofuran 5HT4 agonist, prucalopride, in healthy humans. Gut. 1999 May;44(5):682-6.