Buy Barasertib-HQPA(AZD1152-HQPA)|722544-51-6|DNA damage|from supplier chembestbuy.com|Research only

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CL3116 Barasertib-HQPA(AZD1152-HQPA) (722544-51-6)

Catalog No.:	CL3116
CAS No.:	722544-51-6
Synonym:	AZD2811; INH-34; AZD1152-HQPA
Chemical Name:	2-(5-((7-3-(Ethyl(2-hydroxyethyl)amino)propoxy)quinazolin-4-yl)amino)-1H-pyrazol-3-yl)-N-(3-fluorophenyl)acetamide
Molecular Formula:	C26H30FN7O3
Molecular Weight:	507.56

Technical Data:

Appearance:	White to yellow powder
Solubility:	Soluble in DMSO and Ethanol
Purity:	>99%
Storage:	at -20℃ 2 years
Original QC Data:
Shipping Conditions:	Ambient Temp.

Price and Availability of Barasertib-HQPA(AZD1152-HQPA):

Size	Price	Stock
10 mg	USD 106	In stock
25 mg	USD 186	In stock
50 mg	USD 266	In stock
100 mg	USD 496	In stock

Biological Activity:

AZD 1152-HQPA is a highly potent and selective inhibitor of Aurora B, with Ki values to be 0.36 (Aurora B) and 1.369 nM (Aurora A) respectively and has a high specificity versus a panel of 50 other kinases. The dihydrogen phosphate prodrug, AZD 1152 (Barasertib), is converted rapidly to active AZD1152-HQPA in plasma.

References:

Oke, Adedayo; Pearce, Daniel; Wilkinson, Robert W.; AZD1152 Rapidly and Negatively Affects the Growth and Survival of Human Acute Myeloid Leukemia Cells In vitro and In vivo. Cancer Research (2009), 69(10), 4150-4158.

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