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ICONC14029 Pirarubicin(THP-Adriamycin) (72496-41-4)
 
 
Catalog No.: C14029
CAS No.: 72496-41-4
Synonym: THP-Adriamycin
Chemical Name:
(8s-cis)-droxyacetyl)-1-methoxy;4’-o-tetrahydropyranyladriamycin
Molecular Formula: C32H37NO12
Molecular Weight: 627.64
 
Technical Data:
Appearance:
Solubility: Soluble in DMSO
Purity: >98%
Storage: at -20℃ 2 years
Original QC Data:
Shipping Conditions: Ambient Temp.
 
Price and Availability of Pirarubicin(THP-Adriamycin):

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Biological Activity:
Topoisomerase II inhibitor. Intercalates into DNA and inhibits DNA replication. Analogue of doxorubicin. Expresses anti-tumor activity in vivo.
 
References:

1.Mo G  et al. Influence of coupling bonds on the anti-tumor activity of polymer-pirarubicin conjugates. Eur J Pharm Sci 46:329-35 (2012).

2. Cong W  et al. Characterization and pharmacokinetics of a novel pirarubicin liposome powder. Drug Dev Ind Pharm 36:1186-94 (2010).
 
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