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Pharmacology

Inhibitors

Receptors

Hedgehog Signaling Pathway

Research Area

Cardiovascular System

Product Type

Vitamin D series compounds

Toxins

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C13971 Ozagrel(OKY-046) (82571-53-7)

Catalog No.:

C13971

CAS No.:

82571-53-7

Synonym:

OKY-046

Chemical Name:

(E)-3-[4-(1H-Imidiazol-1-ylmethyl)phenyl]-2-propenic acid

Molecular Formula:

C₁₃H₁₂N₂O₂

Molecular Weight:

228.25

Technical Data:

Appearance:
Solubility:	Soluble in DMSO
Purity:	>98%
Storage:	at -20℃ 2 years
Original QC Data:
Shipping Conditions:	Ambient Temp.

Price and Availability of Ozagrel(OKY-046):

Size	Price	Stock
10mg	USD	In stock
50mg	USD	In stock
100mg	USD	In stock

Biological Activity:

Potent, competitive and selective TXA₂synthetase inhibitor (IC₅₀ = 4 nM). Inhibits platelet aggregation. Shows neuroprotective and anti-ischemic effects in vivo. Orally active.

References:

Sathler PC et al. Human thromboxane synthase: comparative modeling and docking evaluation with the competitive inhibitors Dazoxiben and Ozagrel. J Enzyme Inhib Med Chem : (2013).

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