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C14199 Sunitinib (Sunitinib Base) (557795-19-4)

Catalog No.:	C14199
CAS No.:	557795-19-4
Synonym:	Sunitinib Base
Chemical Name:	N-(2-(Diethylamino)ethyl)-5-((Z)-(5-fluoro-1,2-dihydro-2-oxo-3H-indol-3-ylidene)methyl)-2,4-dimethyl-1H-pyrrole-3-carboxamide
Molecular Formula:	C₂₂H₂₇FN₄O₂
Molecular Weight:	398.47

Technical Data:

Appearance:
Solubility:	Soluble in DMSO and Ethanol
Purity:	99%
Storage:	at -20℃ 2 years
Original QC Data:
Shipping Conditions:	Ambient Temp.

Price and Availability of Sunitinib (Sunitinib Base):

Size	Price	Stock
10mg	USD	In stock
50mg	USD	In stock
100mg	USD	In stock

Biological Activity:

Sunitinib(SU-11248) is a multi-targeted RTK inhibitor targeting VEGFR2 (Flk-1) and PDGFRβ

References:

Sun L, et al. Discovery of 5-[5-fluoro-2-oxo-1,2- dihydroindol-(3Z)-ylidenemethyl]-2,4- dimethyl-1H-pyrrole-3-carboxylic acid (2-diethylaminoethyl)amide, a novel tyrosine kinase inhibitor targeting vascular endothelial and platelet-derived growth factor receptor tyrosine kinase. J Med Chem. 2003 Mar 27;46(7):1116-9.

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