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ICONC11690 Ammothamnine(Oxymatrine) (16837-52-8)
 
 
Catalog No.: C11690
CAS No.: 16837-52-8
Synonym: Oxymatrine; Matrine N-oxide
Chemical Name:
Matrine N-oxide
Molecular Formula: C15H24N2O2
Molecular Weight: 264.36
 
Technical Data:
Appearance:
Solubility: Soluble in DMSO
Purity: >99%
Storage: Store at +4°C
Original QC Data:
Shipping Conditions: Ambient Temp.
 
Price and Availability of Ammothamnine(Oxymatrine):

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10mg 

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50mg 

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100mg 

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Contact us for competitive discounts on bulk quantities

 
Biological Activity:
Natural antiproliferative and apoptotic compound. Inhibits iNOS expression and TGF-β/Smad pathway in bleomycin-induced pulmonary fibrosis. Antitumor, antiviral and anti-arrhythmia agent. Active in vivo and in vitro.
 
References:

1. Liu L  et al. Oxymatrine attenuates bleomycin-induced pulmonary fibrosis in mice via the inhibition of inducible nitric oxide synthase expression and the TGF-ß/Smad signaling pathway. Int J Mol Med 29:815-22 (2012).

2. Song G  et al. Effects of oxymatrine on proliferation and apoptosis in human hepatoma cells. Colloids Surf B Biointerfaces 48:1-5 (2006). 

 
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