ICONHome   ICONContact us   ICONAdd Favorites
Biochemtek
Search Product
Live Chat E-mail
Pharmacology
ICON Inhibitors
ICON Receptors
ICON Hedgehog Signaling Pathway
ICON Stem Cells & Wnt
ICON Signal Transduction
 　 More +
Research Area
ICON Cancer
ICON Antivirus
ICON Cardiovascular System
ICON Endocrinology
ICON Neuroscience
 　 More +
Product Type
ICON Natural Products
ICON Peptides
ICON Prostaglandins
ICON Vitamin D series compounds
ICON Toxins
 　 More +
Browse Alphabetically by Name
ALL A B C D E F
G H I J K L M
N O P Q R S T
U V W X Y Z Others
 
ICONC14271 Eact (461000-66-8)
 
 
Catalog No.: C14271
CAS No.: 461000-66-8
Synonym: TMEM16A Activator, Eact(ANO1 Activator, Eact)
Chemical Name:
3,4,5-Trimethoxy-N-(2-methoxyethyl)-N-(4-phenyl-2-thiazolyl)benzamide
Molecular Formula: C22H24N2O5S
Molecular Weight: 428.5
 
Technical Data:
Appearance:
Solubility: Soluble in DMSO and Ethanol
Purity: >98%
Storage: Store at +4°C
Original QC Data:
Shipping Conditions: Ambient Temp.
 
Price and Availability of Eact:

Size

Price

Stock

10mg 

USD

In Stock 

50mg 

USD

In Stock 

100mg 

USD

In Stock 

Contact us for competitive discounts on bulk quantities
 
Biological Activity:
TMEM16A (ANO1) calcium-activated chloride channel (CaCC) activator (EC50 = 3 μM). Ca2+-independent. Displays no effect on CFTR Cl- or ENaC Na+ conductance. Stimulates submucosal gland secretion in human bronchi.
 
References:
Namkung et al (2011) Small-molecule activators of TMEM16A, a calcium-activated chloride channel, stimulate epithelial chloride secretion and intestinal contraction. FASEB J. 25 4048
 
View Related Products by Target:
LY404039
Pictilisib (GDC-0941)
Triptolide(PG490)
Pirfenidone
GDC-0449(Vismodegib)
Deforolimus(MK-8669)
Temsirolimus (CCI-779, Torisel)
SL 327
PD 184352(CI-1040)
Neratinib(HKI 272)
Sorafenib(Nexavar,Bay43-9006)
Hydroxypropyl-β-cyclodextrin(HPBCD; HPCD)
 
 

Keywords: Buy Eact | Eact Supplier | Purchase Eact | Eact Cost | Eact  Manufacturer | Order Eact | Eact Distributor | Eact Structure, Chembest

Buy 461000-66-8| 461000-66-8 Supplier | Purchase 461000-66-8 | 461000-66-8 Cost | 461000-66-8 Manufacturer | Order 461000-66-8 | 461000-66-8 Distributor | 461000-66-8 Structure, Chembest  
Products are for research use only. Not for human use. We do not sell to patients.
Copyright © 2010-2024 Chembest Research Laboratories. All Rights Reserved
E-mail:sales@biochembest.com