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Cardiovascular System

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Vitamin D series compounds

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CL1995 Bicalutamide (90357-06-5)

Catalog No.:	CL1995
CAS No.:	90357-06-5
Synonym:	Cosudex; Casodex
Chemical Name:	N-[4-Cyano-3-(trifluoromethyl)phenyl]-3-(4-fluorophenyl)sulfonyl-2-hydroxy-2-methyl-propanamide
Molecular Formula:	C₁₈H₁₄F₄N₂O₄S
Molecular Weight:	430.37

Technical Data:

Appearance:	White crystal powder
Solubility:	Soluble in DMSO
Purity:	>99%
Storage:	at -20℃ 2 years
Original QC Data:
Shipping Conditions:	Ambient Temp.

Price and Availability of Bicalutamide:

Size	Price	Stock
1 g	USD 900	In stock
5 g	USD 3800	In stock

Biological Activity:

A nonsteroidal antiandrogen, which has been shown effective in the treatment of prostate cancer. It has also been shown to induce cell death by a pathway that is independent of changes in mitochondrial membrane potential and Bcl-2 actions.

References:

Maucher A, von Angerer E. J Canc Res Clin Oncol. 119:669-74 (1993).
Lee EC, Zhan P, Schallhom R et al. Cell Death &Differentiation. 10:761-71 (2003).

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