Buy LY404039|635318-11-5|Hedgehog Signaling Pathway|from supplier chembestbuy.com|Research only

Home

Add Favorites

Search Product

Live Chat

E-mail

Pharmacology

Inhibitors

Receptors

Hedgehog Signaling Pathway

Research Area

Cardiovascular System

Product Type

Vitamin D series compounds

Toxins

　 More +

Browse Alphabetically by Name

ALL	A	B	C	D	E	F
G	H	I	J	K	L	M
N	O	P	Q	R	S	T
U	V	W	X	Y	Z	Others

CL2391 LY404039 (635318-11-5)

Catalog No.:	CL2391
CAS No.:	635318-11-5
Synonym:	Pomaglumetad
Chemical Name:	(1R,4S,5S,6S)-4-Amino-2-thiabicyclo[3.1.0]hexane-4,6-dicarboxylic acid 2,2-dioxide
Molecular Formula:	C₇H₉NO₆S
Molecular Weight:	235.21

Technical Data:

Appearance:	White or off-white crystalline powder
Solubility:	Soluble in DMSO
Purity:	>99%
Storage:	at -20℃
Original QC Data:
Shipping Conditions:	Ambient Temp.

Price and Availability of LY404039:

Size	Price	Stock
5 mg	USD 56	In stock
10 mg	USD 88	In stock
25 mg	USD 156	In stock
50 mg	USD 269	In stock
100 mg	USD 438	In stock

Biological Activity:

LY-404039 is a drug used in scientific research that acts as a selective agonist for the metabotropic glutamate receptor group II subtypes mGluR2 and mGluR3. It has anxiolytic and antipsychotic effects in animal studies, but without causing sedation. Early human trials using a prodrug form of LY-404,039 called LY-214,0023 have also given encouraging results.

References:

1.Seeman P. An agonist at glutamate and dopamine D2 receptors, LY404039. Neuropharmacology. 2013 Mar;66:87-8.
2. Rorick-Kehn LM, Johnson BG, Knitowski KM, In vivo pharmacological characterization of the structurally novel, potent, selective mGlu2/3 receptor agonistLY404039 in animal models of psychiatric disorders. Psychopharmacology (Berl). 2007 Jul;193(1):121-36.

View Related Products by Target:

Pictilisib (GDC-0941)

Temsirolimus (CCI-779, Torisel)

SL 327

PD 184352(CI-1040)

Neratinib(HKI 272)

Sorafenib(Nexavar,Bay43-9006)

Hydroxypropyl-β-cyclodextrin(HPBCD; HPCD)

Elacridar