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Biological Activity:
A potent, selective, orally bioavailable inhibitor of PI3K and being evaluated in human clinical trials for the treatment of cancer.
References:
Wallin JJ et al.GDC-0941, a novel class I selective PI3K inhibitor, enhances the efficacy of docetaxel in human breast cancer models by increasing cell death in vitro and in vivo.Clin Cancer Res18:3901-11 (2012).