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CL1085 Cyclosporin A (59865-13-3)

Catalog No.:	CL1085
CAS No.:	59865-13-3
Synonym:	Antibiotic S 7481F1; Cyclosporine
Chemical Name:	Cyclosporin A
Molecular Formula:	C₆₂H₁₁₁N₁₁O₁₂
Molecular Weight:	1202.62

Technical Data:

Appearance:	White crystalline powder
Solubility:	Soluble in DMSO and ethanol
Purity:	>99%
Storage:	at -20°C
Original QC Data:
Shipping Conditions:	Ambient Temp.

Price and Availability of Cyclosporin A:

Size	Price	Stock
5 g	USD 168	In stock
10 g	USD 266	In stock
25 g	USD 468	In stock

Biological Activity:

Cyclic oligopeptide with immunosuppressant properties. Induces apoptosis in rat thymocytes and in the murine B cell lymphoma cell line, WEH1-231. However, prevents anti-IgM and ionomycin-induced apoptosis in BLB cell lines. The complex of cyclosporin A wi.

References:

1.Yu DY et al. Effects of cyclosporin A, FK506 and rapamycin on calcineurin phosphatase activity in mouse brain. IUBMB Life 58:429-33 (2006).

2.Ho S et al. The mechanism of action of cyclosporin A and FK506. Clin Immunol Immunopathol 80:S40-5 (1996).

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