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CL2140 Imiquimod(R 837) (99011-02-6)

Catalog No.:	CL2140
CAS No.:	99011-02-6
Synonym:	Aldara;R 837
Chemical Name:	4-Amino- 1-isobutyl-1H-imidazo[4,5-c]quinoline; 1-(2-Methylpropyl)-1H-imidazo[4,5-C]quinolin-4-amine
Molecular Formula:	C₁₄H₁₆N₄
Molecular Weight:	240.3

Technical Data:

Appearance:	White to off-white crystalline powder
Solubility:	Soluble in DMSO and Methanol
Purity:	>99%
Storage:	at -20℃ 2 years
Original QC Data:
Shipping Conditions:	Ambient Temp.

Price and Availability of Imiquimod(R 837):

Size	Price	Stock
250 mg	USD 220	In stock
500 mg	USD 250	In stock
1g	USD 320	In stock

Biological Activity:

Immunomodulator that displays antiviral and antitumor activity. Acts as a Toll-like receptor 7 (TLR-7) agonist; stimulates proinflammatory cytokine production and activates NF-κB.

References:

1. Schön M & Schön MP The antitumoral mode of action of imiquimod and other imidazoquinolines. Curr Med Chem 14:681-7 (2007).

2. Bozrova SV et al. [Imiquimod: the biochemical mechanisms of immunomodulatory and anti-inflammatory activity]. Biomed Khim 59:249-66 (0).

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