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Vitamin D series compounds

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CL1282 NVP-AUY922 (747412-49-3)

Catalog No.:	CL1282
CAS No.:	747412-49-3
Synonym:	VER-52296
Chemical Name:	5-(2,4-Dihydroxy-5-isopropylphenyl)-N-ethyl-4-(4-(morpholinomethyl)phenyl)isoxazole-3-carboxamide
Molecular Formula:	C26H31N3O5
Molecular Weight:	465.55

Technical Data:

Appearance:
Solubility:	Soluble in DMSO and Methanol
Purity:	>99%
Storage:	at +4℃
Original QC Data:
Shipping Conditions:	Ambient Temp.

Price and Availability of NVP-AUY922 :

Size	Price	Stock
50 mg	USD 288	In stock
100 mg	USD 450	In stock
200 mg	USD 766	In stock

Biological Activity:

Highly potent and oral inhibitor of heat shock protein 90 (Hsp90) in vitro and in vivo, with IC50=21 nM in Hsp90 FP binding assay; inhibits proliferation of various human cancer cell lines in vitro, with GI50 average 9 nM.

References:

1.Lee KH, et al. Cancer Sci, 2011, 102(7), 1388-1395.

2. Okui T, et al. Anticancer Res, 2011, 31(4), 1197-1204.

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