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CL1229 Daunorubicin Hydrochloride (23541-50-6)

Catalog No.:	CL1229
CAS No.:	23541-50-6
Synonym:	daunomycin hydrochloride
Chemical Name:	(8S-cis)-8-Acetyl-10-((3-amino-2,3,6-trideoxy-alpha-L-lyxo-hexopyranosyl)oxy)-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-methoxy-5,12-naphthacenedione hydrochloride
Molecular Formula:	C₂₇H₂₉NO₁₀^.HCl
Molecular Weight:	563.99

Technical Data:

Appearance:	Orange red crystalline hygroscopic powder
Solubility:	Slightly soluble in water or methanol, slightly soluble in ethanol (95%). Practically insoluble in chloroform or acetone
Purity:	>99%
Storage:	at -20℃ 2 years
Original QC Data:
Shipping Conditions:	Ambient Temp.

Price and Availability of Daunorubicin Hydrochloride:

Size	Price	Stock
50 mg	USD 216	In stock
100 mg	USD 408	In stock
250 mg	USD 768	In stock

Biological Activity:

An anticancer agent used primarily for the treatment of leukemia. Forms covalent adducts with DNA. Triggers diacylglycerol and ceramide production in tumor cells and induces apoptosis.

References:

1.Bose R, Verheij M, Haimovitz-Friedman A, Ceramide synthase mediates daunorubicin-induced apoptosis: an alternative mechanism for generating death signals. Cell. 1995 Aug 11;82(3):405-14.
2. Fu Y, Zhou J, Li H, Daunorubicin induces procoagulant activity of cultured endothelial cells through phosphatidylserine exposure and microparticles release. Thromb Haemost. 2010 Dec;104(6):1235-41.

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