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ICONCL1120 CP 690550(Tasocitinib) (477600-75-2)
 
 
Catalog No.: CL1120
CAS No.: 477600-75-2
Synonym: Tasocitinib
Chemical Name:

3-{(3R,4R)-4-Methyl-3-[methyl-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-amino]-piperidin-1-yl}-3-oxo-propionitrile

Molecular Formula:

C16H20N6O

Molecular Weight: 312.38
 
Technical Data:
Appearance: white solid
Solubility: Soluble in DMSO and Methanol
Purity: >99%
Storage: at -20℃ 2 years
Original QC Data:
Shipping Conditions: Ambient Temp.
 
Price and Availability of CP 690550(Tasocitinib):

Size

Price

Stock

100 mg 

USD 156

In stock 

250 mg 

USD  238

In stock 

500 mg 

USD 388

In stock 

Contact us for competitive discounts on bulk quantities

 
Biological Activity:

Janus Kinase 3 (JAK3) inhibitor; an immunosuppressive agent exhibiting potent effects in preclinical transplantation and arthritis models; clinically safe and effective in preventing transplant rejection and improving symptoms of rheumatoid arthritis and psoriasis.

 
References:

 Flanagan ME, et al. Discovery of CP-690,550: a potent and selective Janus kinase (JAK) inhibitor for the treatment of autoimmune diseases and organ transplant rejection. J Med Chem, 2010, 53(24), 8468-8484.

 
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