Buy Deforolimus(MK-8669)|572924-54-0|Hedgehog Signaling Pathway|from supplier chembestbuy.com|Research only

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CL1761 Deforolimus(MK-8669) (572924-54-0)

Catalog No.:	CL1761
CAS No.:	572924-54-0
Synonym:	Ridaforolimus;AP23573
Chemical Name:	42-(Dimethylphosphinate)rapamycin
Molecular Formula:	C₅₃H₈₄NO₁₄P
Molecular Weight:	990.21

Technical Data:

Appearance:	White to light yellow powder
Solubility:	Soluble in DMSO
Purity:	>99%
Storage:	at -20℃ 2 years
Original QC Data:
Shipping Conditions:	Ambient Temp.

Price and Availability of Deforolimus(MK-8669):

Size	Price	Stock
25 mg	USD 216	In stock
50 mg	USD 388	In stock
100 mg	USD 698	In stock

Biological Activity:

Deforolimus is an immunosupressant currently undergoing research for the treatment of certain cancers. It is a small-molecule inhibitor of the mammalian target of rapamycin (mTOR).

References:

1.Rivera VM, et al. Ridaforolimus (AP23573; MK8669), a potent mTOR inhibitor, has broad antitumor activity and can be optimally administered using intermittent dosing regimens. Mol Cancer Ther, 2011, 10(6), 1059-1071.
2. Legrier ME, et al. Targeting protein translation in human non small cell lung cancer via combined MEK and mammalian target of rapamycin suppression. Cancer Res, 2007, 67(23), 11300-11308.

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