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ICONC14302 Ubenimex(Bestatin) (58970-76-6 )
 
 
Catalog No.: C14302
CAS No.: 58970-76-6
Synonym: Ubestatin, NK-421, Bestatin
Chemical Name:
N-[(2S,3R)-3-Amino-2-hydroxy-1-oxo-4-phenylbutyl]-L-leucine
Molecular Formula: C16H24N2O4
Molecular Weight: 308.38
 
Technical Data:
Appearance:
Solubility: Soluble in DMSO
Purity: >99%
Storage: Store at +4°C.
Original QC Data:
Shipping Conditions: Ambient Temp.
 
Price and Availability of Ubenimex(Bestatin):

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Biological Activity:

Aminopeptidase inhibitor (Ki = 0.001 - 90 mM); inhibits enkephalin metabolism and leukotriene A4 hydrolase. Inhibits tumor cell proliferation.

 
References:
Chen L  et al. Progress in the development of bestatin analogues as aminopeptidases inhibitors. Curr Med Chem 18:964-76 (2011).
 
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