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ICONC14041 AP24534(Ponatinib) (943319-70-8)
 
 
Catalog No.: C14041
CAS No.: 943319-70-8
Synonym: Ponatinib
Chemical Name:

3-(2-imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-N-[4-[(4-methyl-1-piperazinyl)methyl]-3-(trifluoromethyl)phenyl]-Benzamide
Molecular Formula:

C29H27F3N6O

 
Molecular Weight: 532.56
 
Technical Data:
Appearance: White powder
Solubility: Soluble in DMSO
Purity: >99%
Storage: at -20℃ 2 years
Original QC Data:
Shipping Conditions: Ambient Temp.
 
Price and Availability of AP24534(Ponatinib):

Size

Price

Stock

50mg 

USD80

In Stock 

100mg 

USD150

In Stock 

500mg 

Get quote

 

Contact us for competitive discounts on bulk quantities
 
Biological Activity:

AP24534, a Pan-BCR-ABL Inhibitor for Chronic Myeloid Leukemia, Potently Inhibits the T315I Mutant and Overcomes Mutation-Based Resistance.
 
References:
O'Hare et al (2009) AP24534, a pan-BCR-ABL inhibitor for chronic myeloid leukemia, potently inhibits the T315I mutant and overcomes mutation-based resistance. Cancer Cell 16 401. PMID: 19878872.
 
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