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ICONC13603 Eflornithine hydrochloride (68278-23-9)
 
 
Catalog No.: C13603
CAS No.: 68278-23-9
Synonym: Eflornithine HCl
Chemical Name:
2-(Difluoromethyl)-DL-ornithine monohydrochloride
Molecular Formula:
C6H13ClF2N2O2
Molecular Weight: 218.63
 
Technical Data:
Appearance:
Solubility: Soluble in DMSO and Ethanol
Purity: >99%
Storage: at -20℃ 2 years
Original QC Data:
Shipping Conditions: Ambient Temp.
 
Price and Availability of Eflornithine hydrochloride:

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10mg 

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50mg 

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100mg 

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Contact us for competitive discounts on bulk quantities
 
Biological Activity:
Irreversible inhibitor of ornithine decarboxylase (ODC) that inhibits polyamine biosynthesis. Displays antiapoptotic, antiangiogenic and antiparasitic activity. Induces re-expression of aberrantly silenced tumor suppressor genes when used in combination with oligoamine analogs.
 
References:

Raul (2007) Revival of 2-(difluoromethyl)ornithine (DFMO), an inhibitor of polyamine biosynthesis, as a cancer chemopreventative agent. Biochem.Soc.Trans. 35 353.
 
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